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Tyloxapol Chemical

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  • Phenol,4-(1,1,3,3-tetramethylbutyl) polymer with formaldehyde and oxirane
  • meets JPC and USP specifications
  • yellow-brown viscous liquid
  • soluble in polar and non-polar solvents
  • Non-ionic liquid polymer
  • US-produced product
  • Consistent quality, convenient packaging
  • CAS# 25301-02-4
  • Used as a surfactant, detergent, dispersing agent, encapsulating agent, hydroxy radical scavenger
  • Modifies interfacial tension of water
  • Forms stable dispersions of nanoparticles

Some relevant literature;

Encapsulation of sensitive liquid components into a matrix to obtain discrete shelf-stable particles. Van Lengerich, Bernhard H. (General Mills, Inc., USA). PCT Int. Application (2000), 56 pp. WO 2000021504

Tyloxapol inhibits NF-kappa B and cytokine release, scavenges HOCI, and reduces viscosity of cystic fibrosis sputum. AJ Ghio, BC Marshall, JL Diaz, T Hasegawa, W Samuelson, D Povia, TP Kennedy and CA Piantodosi. Am. J. Respir. Crit. Care Med., Vol 154, No. 3, Sep 1996, 783-788.

Polymeric surfactants for enhanced oil recovery. Part III. Interfacial tension features of ethoxylated alkylphenol-formaldehyde nonionic surfactants. Barakat, Y.; Basily, I. K.; Mohamad, A. I.; Youssef, A. M. British Polymer Journal (1989), 21(6), 459-65

Use of PEG-derivatized lipids as surface stabilizers for nanoparticulate compositions. Liversidge, Elaine; Gottardy, Greta A. (Nanosystems, USA). PCT Int. Application (2000), 41 pp. WO 2000051572

Method for the production of porous particles. Chattopadhyay, Pratibhash; Shekunov, Boris Y.; Gibson, Adam K. (Ferro Corporation, USA). U.S. Pat. Application Pub (2007), 8pp. US 2007275076

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